cover
Article Per Year (5 Year)
All
Home Page
OAI Link
Editorial Team
Contact
Reviewer
Google Scholar
Contact Name
-
Contact Email
-
Phone
-
Journal Mail Official
-
Editorial Address
-
Location
Kota surabaya,
Jawa timur
INDONESIA
Indonesian Journal of Tropical and Infectious Disease
Published by Universitas Airlangga
ISSN : 20851103     EISSN : 23560991     DOI : -
Core Subject : Health, Science,
Earth & Planetary Sciences Health Professions Medicine & Pharmacology Public Health
This journal is a peer-reviewed journal established to promote the recognition of emerging and reemerging diseases specifically in Indonesia, South East Asia, other tropical countries and around the world, and to improve the understanding of factors involved in disease emergence, prevention, and elimination. The journal is intended for scientists, clinicians, and professionals in infectious diseases and related sciences. We welcome contributions from infectious disease specialists in academia, industry, clinical practice, public health, and pharmacy, as well as from specialists in economics, social sciences and other disciplines.
Arjuna Subject : -
Articles 8 Documents
 1 
Search results for , issue "Vol. 11 No. 1 (2023)" : 8 Documents clear
Germ Tube Induction Test Comparing Total of Six Liquid and Three Solid Media in Candida albicans Rivaldi Ruby; Erlangga Saputra Arifin; Sandy Vitria Kurniawan; Sem Samuel Surja
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.34097

Abstract

Invasive candidiasis (IC) has a high mortality rate of 70%, thus diagnosis should be established without delay. Given its fast result, serological test such as β-d-glucan (BDG) test is one alternative diagnosis modalities. However, it lacks specificity. Candida albicans germ tube antibody (CAGTA) test is an alternative serological test which has a high sensitivity of 76.2% and specificity of 80.3%.  Manufacturing CAGTA serological test requires provision of specific germ tube antigen. In this study, various culture media were tested to find the best media for germ tube induction. This study was an experimental in vitro study. The number and length of the germ tube were recorded in two- and three-hour incubation periods. A total of six samples containing one C. albicans ATCC 90028, four C. albicans wild type strains, and one C. krusei wild type strain were used. Nine media were tested to induce germ   tube formation: human and sheep serum, fetal bovine serum, mueller hinton agar and broth, tryptic soy agar and broth, brain heart infusion agar and broth. At both incubation periods, the medium with the highest number of germ tube was human serum (p=0.001 and p=0). The longest germ tube was found in sheep serum at two-hour incubation period (p=0.005). Mueller hinton broth (MHB) showed comparable results with human and sheep serum (p>0.05). Human serum is a superior inducer of morphogenesis. However, the use of MHB is recommended in this study, since provision of fresh human and sheep serum on a regular basis is impractical.
Electronic Nose (E-Nose) for Quality Detection of Tuna (Thunnus thynnus) Contaminated Bacteria Suryani Dyah Astuti; Alfian Baggraf Muhamad; Akif Rahmatillah; Ahmad Khalil Yaqubi; Yunus Susilo; Angger Krisna Aji
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.39206

Abstract

Tuna (Thunnus thynnus) is a food that is often consumed raw to support raw food diet activities, so it has the potential to be contaminated with Salmonella typhi bacteria. Fish can be contaminated by bacteria due to their high water and protein content. Indonesia is the world's main tuna producer. Salmonella typhi detection in fresh tuna in Indonesia must be negative for Salmonella microbial contamination in order to meet food safety requirements. Microbial testing has drawbacks, such as long delays. An electronic nose was used to detect Salmonella typhi bacteria in tuna fish. The sample used consisted of 3 kinds of samples: Salmonella typhi bacteria, tuna, and tuna with Salmonella typhi contamination. The research was conducted with a shelf life of 48 hours and a sensing period every 6 hours with a sensor array of 8 sensors. The sensor output data is processed using the PCA (Principal Component Analysis) method. Through the PCA method, each variation of bacterial treatment can be classified. The result of the cumulative percentage variance of the two main components (PC) in the classification test between Salmonella typhi, tuna, and tuna with Salmonella typhi bacteria contamination was 90.5%. The most influential sensors in this study are TGS 825 for PC1 with a loading value of 0.625 and TGS 826 for PC2 with a loading value of -0.753. Therefore, it can be concluded that an electronic nose can classify between pure tuna and tuna contaminated with Salmonella typhi bacteria.
Severe Leptospirosis (Weil’s Disease) with Multiple Organ Failure in Urban Setting: A Case Report Samuel Halim; Bryan Arista Hartono
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.39466

Abstract

Leptospirosis is a rare disease that could cause multiple organ failures and death if left untreated. The correct treatment will determine the recovery of patients. A 28-years old male came to the Emergency Department with profuse diarrhea. No prior medical history; worked as a private employee recently assigned to collect rat traps one week before. Laboratories show severe thrombocytopenia, acute liver failure, and acute renal failure support by imaging with the conclusion of hepatomegaly with normal kidney size. During observation in the emergency room, the patient worsens into septic shock. The patient was treated in intensive care, diagnosed with Weil's disease, and treated given antibiotics with aggressive fluid therapy; dialysis was postponed, and close monitoring of the patient's symptoms and organ function. After five days of care, clinical symptoms and organ function improved, and the patient was discharged well. Diagnosis of Leptospirosis is challenging with a combination of signs and symptoms that are not commonly found. Therefore, primary treatment is antibiotic and supportive care such as renal replacement therapy is not routinely needed as long there are improvements in close monitoring. This objective is to increase awareness and treatment option for further severe leptospirosis cases
Acute Acalculous Cholecystitis Associated with Hepatitis A Viral Infection: A Case Report Bonfilio Neltio Ariobimo; Nurun Nujum; Daniel Ponco Harto Saputro
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.39532

Abstract

Most hepatitis A infections are acute, self-limiting, and asymptomatic. In rare instances, extra hepatic complication, such as acute cholecystitis, may emerge. Acute cholecystitis is inflammation of the gallbladder wall and is classified into calculus and acalculus. About 90–95% of cases are brought on by bile duct stones. Acute acalculous cholecystitis can be brought on by structural and functional abnormalities in the gallbladder brought on by viral hepatitis infection. Here we present a 20 years old female patient with acute acalculous cholecystitis associated with hepatitis A infection. Gallbladder distention, thickening of the gallbladder wall, absence of acoustic shadow or biliary sludge, perivesical liquid buildup, and absence of dilatation of the intra- and extrahepatic bile ducts are among the ultrasonographic criteria for diagnosing acute acalculous cholecystitis. The viral hepatitis serology revealed acute hepatitis A infection with positive anti-HAV IgM. Hepatitis A testing should be considered in patients suspected with acalculous cholecystitis of undefined etiology in markedly deranged liver function test adult patients.
Impact of Hypertension and Cardiovascular Diseases to Immune Response in COVID-19 Vaccination: A Systematic Review Karin Dhia Fahmita; Gatot Soegiarto; Laksmi Wulandari; Dewajani Purnomosari
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.40266

Abstract

To determine impact of hypertension and cardiovascular diseases towards effectivity and safety of COVID-19 vaccination. Systematic review based on PRISMA statement was done. Searching was conducted in PubMed, ScienceDirect, Scopus, and ProQuest and resulting in 6 studies involving 4,053 participants which deemed on good quality according to Joanna Briggs Institute tools for critical appraisal. After thorough analysis, we found that two out of four studies assessing mRNA-based vaccine found out that hypertension lower antibody response significantly. Two out of two studies assessing inactivated virus vaccine shown that hypertensive patients tend to have lower antibody titers compared to control. One of studies mentioned above found that antibody titer was not different between populations with cardiovascular diseases and control.Hypertension lessened response to COVID-19 vaccination regardless of vaccine type used. However, lack of studies on cardiovascular disease suggested that more studies should be conducted, along with hypertension, in-order to make meta-analysis possible to provide better evidence.
Portable and Battery-Operated Isothermal Amplification Device Validation for Onsite Analysis of M. tuberculosis “DNA Hunter” H. Esra Agel
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.40482

Abstract

Point-of-care (POC) devices play an important role in the protection of public health by providing rapid diagnosis of infectious diseases, patient management, and effective treatment. Fast, easy-to-interpret, environmentally resistant, and cost-effective POC tests that can be used practically in the field are gaining more and more importance every day. There is a need for portable devices that will enable rapid diagnosis kits to be used in the field for early diagnosis and treatment. The aim of this study is to evaluate the DNA hunter device that was developed in terms of providing the required temperature for M. tuberculosis (MTB) diagnosis of the loop-mediated isothermal amplification (LAMP) assay and visually evaluating the analysis results. The device in this study; handheld (total weight 430 g, outer dimensions 70 x 175 x 80 mm), the average operating time can reach a maximum temperature of 110 degrees in 2 minutes with a fully charged battery, and the processing time is about 90 minutes without being connected to electricity. It can display the pre-evaluation result on the screen with the full digital color sensor. The device can be adjusted to the desired reaction temperature and time. It also has software where sample registration numbers can be entered. DNA Hunter can be used for all analyses performed by the LAMP method and the results can be evaluated colorimetrically, thus it is well suited for POC testing.
Moringa oleifera Leaf Ethanol Extract Inhibits Toxoplasma gondii Tachyzoites Replication Laura Wihanto; Gladdy Lysias Waworuntu; Cecilia Putri Tedyanto; Heni Puspitasari
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.42672

Abstract

The various infection routes of Toxoplasma gondii that are close to daily life strongly support the incidence of toxoplasmosis. The emergence of drug-resistant Toxoplasma gondii strains raises future concerns. Moringa leaf ethanol extract has been shown to have several anti-pathogen activities, which could have an anti-Toxoplasma effect. This research was conducted to analyze the anti-Toxoplasma effect of moringa leaf ethanol extract against tachyzoites replication in Toxoplasma gondii and the correlation between extract doses with the number of tachyzoites. Mice were divided into five groups. The negative control group (Group I) received CMC-Na solution. The positive control group (Group II) received spiramycin 100 mg/kg BW. The treatment groups received moringa leaf ethanol extract 250 mg/kg BW (group III), 500 mg/kg BW (group IV), and 1000 mg/kg BW (group V), respectively. Mice were injected with 1 x 105 tachyzoites/0.1 mL/mice intraperitoneally on the first day. Moringa leaf ethanol extract and spiramycin were given orally once daily for three days. The number of tachyzoites in the intraperitoneal fluid was calculated on the fifth day. The results have shown that there were significantly lower differences (P < 0.05) in group IV (P = 0.021) and group V (P = 0.022) compared to group I. There was also a significant negative correlation between the extract doses and the number of tachyzoites (P = 0.000; r = -0.781). Moringa oleifera leaf ethanol extract has an anti-Toxoplasma effect by inhibiting the tachyzoite replication at     500 mg/kg BW and 1000 mg/kg BW.
Epidemiological and Clinical Features of Critical and Non-Critical Elderly COVID-19 Patients in Udayana University Academic Hospital: A Retrospective Study Cokorda Agung Wahyu Purnamasidhi; I Ketut Agus Somia; Darren Junior; Richard Christian Suteja; I Komang Hotra Adiputra; Giovanca Verentzia Purnama; I Gede Purna Weisnawa; Jerry; Putu Kintan Wulandari; Dewa Ayu Fony Prema Shanti; I Gusti Ngurah Ariestha Satya Diksha
Indonesian Journal of Tropical and Infectious Disease Vol. 11 No. 1 (2023)
Publisher : Institute of Topical Disease Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/ijtid.v11i1.43097

Abstract

Elderly COVID-19 patients have been associated with worse outcomes and have been presented with the highest mortality rate. However, studies on the clinical features and the differences between critical and non-critical elderly COVID-19 patients in Indonesia and even other countries are still lacking and rare. In this retrospective study, the epidemiological and clinical features of critical and non-critical elderly COVID-19 patients admitted to Udayana University Academic Hospital between April 2020 and March 2021 were analyzed and then compared. Of the 280 medical records analyzed, 60.7% were male and the median age was 65.0 years old. Based on the medical records, 18.2% of elderly patients met our criteria of critical patients. The most common symptoms presented in both category upon admission included fever and coughing. The most common comorbidity found in critical patients was heart disease and hypertension in non-critical patients. Laboratory results differences included leukocytes, neutrophils, lymphocytes, Neutrophil-to-Lymphocyte Ratio, platelets, SGOT, SGPT, and urea. Only 9.9% of critical patients and 6.1% of non-critical patients were given antiviral therapy. In contrast, 68.6% of critical patients and 76% of non-critical patients were given antibiotics. The mortality rate in critical patients was 70.6% and 0.4% in non-critical patients. Based on the results, a multimodal approach in the treatment of elderly COVID-19 patients is very essential. The higher mortality rate in elderly patients should be able to be reduced by giving early and timely antiviral therapy with the addition of effective choice of drugs.

Page 1 of 1 | Total Record : 8

 1 

Filter by Year

2023 2023


Reset
Filter By Issues
All Issue Vol. 11 No. 2 (2023) Vol. 11 No. 1 (2023) Vol. 10 No. 3 (2022) Vol. 10 No. 2 (2022) Vol. 10 No. 1 (2022) Vol. 9 No. 3 (2021) Vol. 9 No. 2 (2021) Vol. 9 No. 1 (2021) Vol. 8 No. 3 (2020) Vol. 8 No. 2 (2020) Vol. 8 No. 1 (2020) Vol. 7 No. 6 (2019) Vol. 7 No. 5 (2019) Vol. 7 No. 4 (2019) Vol. 7 No. 3 (2018) Vol. 7 No. 2 (2018) Vol. 7 No. 1 (2018) Vol. 6 No. 6 (2017) Vol. 6 No. 5 (2017) Vol. 6 No. 4 (2017) Vol. 6 No. 3 (2016) Vol. 6 No. 2 (2016) Vol. 6 No. 1 (2016) Vol 5, No 7 (2015) Vol. 5 No. 6 (2015) Vol 5, No 6 (2015) Vol 5, No 5 (2015) Vol. 5 No. 5 (2015) Vol. 5 No. 4 (2015) Vol 5, No 3 (2014) Vol. 5 No. 3 (2014) Vol 5, No 2 (2014) Vol. 5 No. 2 (2014) Vol. 5 No. 1 (2014) Vol 5, No 1 (2014) Vol 4, No 4 (2013) Vol. 4 No. 4 (2013) Vol. 3 No. 2 (2012) Vol 3, No 2 (2012) Vol. 3 No. 1 (2012) Vol 3, No 1 (2012) Vol 2, No 1 (2011) Vol. 2 No. 1 (2011) Vol. 1 No. 3 (2010) Vol. 1 No. 2 (2010) Vol 1, No 1 (2010) Vol. 1 No. 1 (2010) More Issue